Exclusive Week 10 NFL Betting Predictions and Picks from VSiN

Week 10 of the NFL is presenting some challenging betting scenarios with closely-lined games and a high degree of inconsistency across teams. Injuries at various positions are also impacting the odds, adding to the complexity of making betting decisions. Here are some of the best bets for Week 10, as of November 9:

49ers vs. Jaguars: Despite the 49ers coming off a bye week with some key players returning, the Jaguars present a strong defensive challenge, ranking third in the NFL by EPA/play, 4th in Dropback EPA, and 12th in Rush EPA defense. The 49ers are expected to see improvements on defense, especially with the addition of Chase Young. With a lower scoring game in mind, the pick is to bet under 45.

Raiders vs. Jets: The Raiders demonstrated a significant improvement in their performance last week, winning their first game without Josh McDaniels. The team rallied behind interim head coach Antonio Pierce and secured a victory against the Giants. Despite the Jets having a solid defense, their offense ranks as the worst in the league, making the Raiders a favorable pick. The choice is to bet on the Raiders at a pick ’em, playing to -1.5.

The complex betting landscape in Week 10 of the NFL requires careful consideration of various factors before making wagers. These picks reflect the expert analysis of the matchups and odds for the upcoming games.